TK'ers would all be played by the Muppets.
ROTF I never thought of it but mm really has something Miss Piggy-ish in her posting style and Bickendan would make a nice Kermit. I'd cast Miller as Robin, Loktar and Dork as Stratler and Waldorf. Bunsen Honeydew and Beaker would be Consumer and Seph. ESAD is Sweetums, Consumer is the vampire (sorry, I forgot his name).
Dead-serious Sam the Eagle can't be anyone but Daystrom, Scooter would be Hambil, Fozzy Bear is Miller, Gonzo the Great is 'Gear. Myself would propably be Rizzo the Rat.
In the movie of my life I'd cast
Katherine Hepburn as the heroine
John Wayne and Jim Byrnes as Daystrom and Santaman, the heroine's supporting RL-friends
Margaret Rutherford as another RL-friend (whos name won't be told as she is no member here)
David Niven and Maggie Smith as the parents
Peter Sellers and Sigourney Weaver as the siblings
Peter Wingfield as the current love interest
Stan Laurel and Oliver Hardy as Blooded and Red Whacker, the involuntarily funny villains
Roger Daltrey as the boss
Paris Hilton as the unnervingly stupid colleague
15 male and 4 female more or less handsome actors/actresses as the ex-lovers (definitely including Stan Kirsch, Johnny Depp and Sean Connery, Valentine Pelka, Werner Stocker, Dietmar Schönherr, Von Flores, Hugh Jackman, Julian McMahon, Kitty Swink and Hale Berry)
Plus some 300 extras for postmen, shopkeepers, landladies, neighbours and other recurring characters.